Research laboratories

We aim to better understand host-virus interactions to prevent, detect and fight virus-induced diseases.
We especially work on infection by retroviruses and arboviruses to:
• understand the molecular determinants of infection, pathogenicity and transmission
• study the virus- host (mammals, insects) dialogue and the host response to infection
• develop new tools for field diagnosis and antiviral molecules.

In collaboration with clinicians and veterinarians, we develop "comparative pathology" projects, especially in the lung, by using spontaneous animal cancers to understand human rare cancers.

Our expertise allows us to develop cellular and molecular approaches, in vitro, in insecto as well as in vivo using 3D cell system, organoid tissue culture or tissue sections. We use Drosophila as genetic model and viral vectors or microvesicles as antiviral or therapeutic targeting tools.

Our activity is divided into 4 teams, defining two lines of research:

• Virus and thoracic pathology:
  • Physiopathology, Retroviruses and Rare Tumors
  • Microvesicles, Pathogenesis and Therapeutic Targeting
• Emerging zoonoses and vector-borne diseases:
  • Biology of phleboviruses
  • Transmission of alphaviruses and comparative pathology