UMR_C 8576 - Structural and functional glycobiology (UGSF)

The study of the structure and function of complex carbohydrates associated with proteins or free polysaccharides as well as the enzymes involved in their biosynthesis and degradation are at the heart of the unit's research projects. These aim to establish the link between the structure and function of glycannes, experimental approaches are multiple combining genetics, molecular biology, cell biology, biochemistry, physico-chemistry as well as biological models (from prokaryotic and eukaryotic microorganisms to animals and plants).

The unit's themes cover a broad spectrum of interests ranging from the glycobiology of microorganisms, plant glycobiology to human health issues (glycopathologies).

Research teams

  • Computational Molecular Systems Biology 
  • Diversity of heparan sulfates and regulation of the inflammatory response 
  • Genetic of the Bacterial envelope 
  • Glycobiology of olfaction 
  • Glycobiology of stress-related disorders 
  • Microbial genetics 
  • Molecular mechanisms of N-glycosylation and associated diseases 
  • NMR & Molecular Interactions 
  • O-GlcNAcylation, cell signaling and cell cycle 
  • Plant fibers 
  • Plant glycobiology
  • Regulation of Division Signal 
  • Regulation of terminal glycosylation 
  • Structural and integrative biology 
  • Structural glycobiology of host-pathogen interactions 

Key figures :

130 staff